2139-03-9
2139-03-9 structure
- Name: Pyrroline-5-carboxylate
- Chemical Name: 1-pyrroline-2-carboxylic acid
- CAS Number: 2139-03-9
- Molecular Formula: C5H7NO2
- Molecular Weight: 113.11500
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-08-27 13:15:51
- Modify Date: 2024-01-08 14:39:37
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Pyrroline-5-carboxylate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 1-pyrroline-2-carboxylic acid |
|---|---|
| Synonyms |
d1-Pyrroline 2-carboxylate
3,4-DIHYDRO-2H-PYRROLIUM-5-CARBOXYLATE 4,5-dihydro-3H-pyrrole-2-carboxylic acid delta1-Pyrroline 2-carboxylate 1-Pyrroline-2-carboxylic acid 4,5-Dihydro-3H-pyrrol-2-carbonsaeure 3,4-dihydro-2H-pyrrole-5-carboxylic acid 1-Pyrrolin-2-carbonsaeure 1-Pyrroline-2-carboxylate |
| Description | Pyrroline-5-carboxylate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.35g/cm3 |
|---|---|
| Boiling Point | 255.5ºC at 760mmHg |
| Molecular Formula | C5H7NO2 |
| Molecular Weight | 113.11500 |
| Flash Point | 108.3ºC |
| Exact Mass | 113.04800 |
| PSA | 49.66000 |
| Vapour Pressure | 0.00498mmHg at 25°C |
| Index of Refraction | 1.58 |
| HS Code | 2933990090 |
|---|
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |