179030-22-9
179030-22-9 structure
- Name: NAG-thiazoline
- Chemical Name: (3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol
- CAS Number: 179030-22-9
- Molecular Formula: C8H13NO4S
- Molecular Weight: 219.26
- Catalog: Signaling Pathways Anti-infection Bacterial
- Create Date: 2016-01-04 05:57:42
- Modify Date: 2024-01-21 22:11:53
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NAG-thiazoline is a O-GlcNAcase inhibitor with a Ki of 180 nM. NAG-thiazoline is a potent GH20 GlcNAcase (VhGlcNAcase) inhibitor with an IC50 of 11.9 μM and a Ki of 62 µM[1].
| Name | (3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol |
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| Synonyms |
(3aR,5R,6S,7R,7aR)-5-(Hydroxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol
3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL (5R,6S,7R)-5-(Hydroxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol NAG-thiazoline 5H-Pyrano[3,2-d]thiazole-6,7-diol, 3a,6,7,7a-tetrahydro-5-(hydroxymethyl)-2-methyl-, (5R,6S,7R)- N-Acetylglucosamine Thiazoline UNII-ML5FHL557A 2epn NGT 1hp5 5H-Pyrano[3,2-d]thiazole-6,7-diol, 3a,6,7,7a-tetrahydro-5-(hydroxymethyl)-2-methyl-, (3aR,5R,6S,7R,7aR)- |
| Description | NAG-thiazoline is a O-GlcNAcase inhibitor with a Ki of 180 nM. NAG-thiazoline is a potent GH20 GlcNAcase (VhGlcNAcase) inhibitor with an IC50 of 11.9 μM and a Ki of 62 µM[1]. |
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| Related Catalog | |
| References |
| Density | 1.8±0.1 g/cm3 |
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| Boiling Point | 443.0±45.0 °C at 760 mmHg |
| Molecular Formula | C8H13NO4S |
| Molecular Weight | 219.26 |
| Flash Point | 221.7±28.7 °C |
| Exact Mass | 219.056534 |
| PSA | 107.58000 |
| LogP | -0.44 |
| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
| Index of Refraction | 1.742 |