148171-35-1

148171-35-1 structure

Name: 6-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine
Chemical Name: N7-(2'-deoxy-β-D-erythro-pentofuranosyl)adenine
CAS Number: 148171-35-1
Molecular Formula: C₁₀H₁₃N₅O₃
Molecular Weight: 251.24
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-11-22 14:57:21
Modify Date: 2024-01-12 17:14:18
6-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	N7-(2'-deoxy-β-D-erythro-pentofuranosyl)adenine
Synonyms	7-(2-deoxy-β-D-erythro-pentofuranosyl)adenine 7-(2'-deoxy-β-D-ribofuranosyl)adenine 7-[2-deoxy-β-D-erythro-pentofuranosyl]-7H-adenine 2'-deoxy-3-isoadenosine

Description	6-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.