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61337-87-9

61337-87-9 structure
61337-87-9 structure
  • Name: (S)-Mirtazapine-13C-d3
  • Chemical Name: (+)-Mirtazapine
  • CAS Number: 61337-87-9
  • Molecular Formula: C17H19N3
  • Molecular Weight: 265.353
  • Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
  • Create Date: 2016-01-18 07:38:18
  • Modify Date: 2024-01-09 07:58:34
  • (S)-Mirtazapine ((S)-Org3770) is a S(+)-enantiomer of Mirtazapine with pronociceptive properties in an animal model of acute thermal nociception. (S)-Mirtazapine is a stereoselective 5-HT2 receptor antagonist. (S)-Mirtazapine is metabolized by CYP2D6 and CYP1A2[1].

Name (+)-Mirtazapine
Synonyms mirtazapine
(14bS)-2-Methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
(14b,S)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
(S)-mirtazepine
(S)-1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine
Esmirtazapine
ORG-50,081
Pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl-, (14bS)-
(S)-(+)-MIRTAZAPINE
(S)-1,2,3,4,10,14b-hexahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
(S)-1,2,3,4,10,14b-hexahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3c][2]benzazepine
(S)1,2,3,4,10,14b-hexahydro-2-methyl-pyrazino-[2,1-a] pyrido [2,3-c] [2] benzazepin
Description (S)-Mirtazapine ((S)-Org3770) is a S(+)-enantiomer of Mirtazapine with pronociceptive properties in an animal model of acute thermal nociception. (S)-Mirtazapine is a stereoselective 5-HT2 receptor antagonist. (S)-Mirtazapine is metabolized by CYP2D6 and CYP1A2[1].
Related Catalog
Target

5-HT2 receptor[1]

References

[1]. Muth-Selbach U, et al. Racemic intrathecal mirtazapine but not its enantiomers acts anti-neuropathic after chronic constriction injury in rats. Brain Res Bull. 2009 Apr 6;79(1):63-8.

Density 1.2±0.1 g/cm3
Boiling Point 432.4±45.0 °C at 760 mmHg
Molecular Formula C17H19N3
Molecular Weight 265.353
Flash Point 215.3±28.7 °C
Exact Mass 265.157898
PSA 19.37000
LogP 2.75
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.668
HS Code 2933990090
Precursor  0

DownStream  1

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%