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299430-87-8

299430-87-8 structure

299430-87-8 structure

Name: Fmoc-N-amido-PEG2-alcohol
Chemical Name: 9H-fluoren-9-ylmethyl N-[2-(2-hydroxyethoxy)ethyl]carbamate
CAS Number: 299430-87-8
Molecular Formula: C₁₉H₂₁NO₄
Molecular Weight: 327.37400
Catalog: Biochemical Amino acids and their derivatives Amino alcohol derivative
Create Date: 2018-12-08 17:19:18
Modify Date: 2026-08-06 20:49:54
Fmoc-N-amido-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	9H-fluoren-9-ylmethyl N-[2-(2-hydroxyethoxy)ethyl]carbamate
Synonyms	CAS_299-8 Cbamic acid, N-[2-(2-hydroxyethoxy)ethyl]-, 9H-fluoren-9-ylmethyl ester 2-[2-(Fmoc-amino)ethoxy]ethanol (HPLC) [2-(2-Hydroxy-ethoxy)-ethyl]-cbamic acid 9H-fluoren-9-ylmethyl ester 2-[2-(Fmoc-amino)ethoxy]ethanol Fmoc-5-amino-3-oxa-1-pentanol AmbotzFAL3010 Fmoc-NH-PEG2-OH (9H-Fluoren-9-yl)methyl (2-(2-hydroxyethoxy)ethyl)cbamate FMOC-2-(2-AMINOETHOXY)ETHANOL Fmoc-NH-PEG2-alcohol N-Fmoc-2-(2-hydroxyethoxy)ethanamine [2-(2-Hydroxy-ethoxy)ethyl]cbamic acid 9H-fluoren-9-ylmethyl ester FMOC-2-(2-AMINOETHOXY)ETHANOL //BP 9H-fluoren-9-ylmethylN-[2-(2-hydroxyethoxy)ethyl]cbamate

Description	Fmoc-N-amido-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density	1.221g/cm3
Boiling Point	547.8ºC at 760 mmHg
Molecular Formula	C₁₉H₂₁NO₄
Molecular Weight	327.37400
Flash Point	285.1ºC
Exact Mass	327.14700
PSA	67.79000
LogP	2.92490
Vapour Pressure	7.81E-13mmHg at 25°C
Index of Refraction	1.588
Storage condition	2-8°C

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

28920-43-6 structure

28920-43-6

929-06-6 structure

929-06-6

~96%

299430-87-8 structure

299430-87-8

Literature: Nasopoulou, Magdalini; Georgiadis, Dimitris; Matziari, Magdalini; Dive, Vincent; Yiotakis, Athanasios Journal of Organic Chemistry, 2007 , vol. 72, # 19 p. 7222 - 7228

Precursor 2
28920-43-6 929-06-6
DownStream 0

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