19916-77-9

19916-77-9 structure
19916-77-9 structure
  • Name: 2′-Deoxy-N-methylguanosine
  • Chemical Name: (2R,3S,5R)-5-(2-amino-6-methoxypurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
  • CAS Number: 19916-77-9
  • Molecular Formula: C11H15N5O4
  • Molecular Weight: 281.27
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2016-07-16 02:54:54
  • Modify Date: 2024-01-02 16:26:58
  • 2’-Deoxy-N2-methylguanosine, DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name (2R,3S,5R)-5-(2-amino-6-methoxypurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
Synonyms N2-methyl-2'-deoxy-guanosine
2'-deoxy-2-N-methylguanosine
O6-Methyl-dG
Description 2’-Deoxy-N2-methylguanosine, DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Molecular Formula C11H15N5O4
Molecular Weight 281.27
Exact Mass 281.11200
PSA 125.29000
Precursor  1

DownStream  0