63968-75-2

63968-75-2 structure

63968-75-2 structure

Name: 4-chloro-N-(2-methylindol-1-yl)-3-sulfamoylbenzamide
Chemical Name: 4-chloro-N-(2-methylindol-1-yl)-3-sulfamoylbenzamide
CAS Number: 63968-75-2
Molecular Formula: C₁₆H₁₄ClN₃O₃S
Molecular Weight: 363.81900
Catalog: analytical chemistry Standard Pharmacopoeia Standards and Magazine Standards
Create Date: 2016-11-26 23:47:40
Modify Date: 2024-02-01 10:40:29

Name	4-chloro-N-(2-methylindol-1-yl)-3-sulfamoylbenzamide
Synonyms	N-(3-sulfamyl-4-chlorobenzamido)-2-methylindole 4-Chloro-N-(2-methyl-1-indolyl)-3-sulfamoylbenzamide Benzamide,3-(aminosulfonyl)-4-chloro-N-(2-methyl-1H-indol-1-yl) BENZAMIDE,4-CHLORO-N-(2-METHYL-1-INDOLYL)-3-SULFAMOYL Dehydroindapamide Indapamide Impurity 2

Density	1.49g/cm3
Melting Point	255-257℃
Molecular Formula	C₁₆H₁₄ClN₃O₃S
Molecular Weight	363.81900
Exact Mass	363.04400
PSA	102.57000
LogP	4.48850
Index of Refraction	1.687

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV2451500

CHEMICAL NAME :: Benzamide, 4-chloro-N-(2-methyl-1-indolyl)-3-sulfamoyl-

CAS REGISTRY NUMBER :: 63968-75-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C16-H14-Cl-N3-O3-S

MOLECULAR WEIGHT :: 363.84

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 16,2275,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 620 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 16,2275,1982

RIDADR	NONH for all modes of transport
HS Code	2935009090

26807-65-8 structure

26807-65-8

~51%

63968-75-2 structure

63968-75-2

Literature: O'Hare; Tan; Rehm; et al. Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 3 p. 819 - 820

53406-41-0 structure

53406-41-0

70049-77-3 structure

70049-77-3

~%

63968-75-2 structure

63968-75-2

Literature: Journal of Heterocyclic Chemistry, , vol. 20, # 3 p. 819 - 820

Precursor 3
26807-65-8 53406-41-0 70049-77-3
DownStream 0

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%