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185039-48-9

185039-48-9 structure
185039-48-9 structure

Name 6-(2,6-Dichlorophenyl)-8-methyl-2-methylsulfonyl-8H-pyrido[2,3-d]pyrimidin-7-one
Synonyms Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(2,6-dichlorophenyl)-8-methyl-2-(methylsulfonyl)-
6-(2,6-Dichlorophenyl)-8-methyl-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-one
6-(2,6-dichlorophenyl)-8-methyl-2-methylsulfonylpyrido[2,3-d]pyrimidin-7-one
Density 1.5±0.1 g/cm3
Boiling Point 588.4±60.0 °C at 760 mmHg
Molecular Formula C15H11Cl2N3O3S
Molecular Weight 384.237
Flash Point 309.7±32.9 °C
Exact Mass 382.989807
PSA 90.30000
LogP 1.39
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.638

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185039-48-9 structure

185039-48-9

Literature: SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH Patent: WO2004/63195 A1, 2004 ; Location in patent: Page 53; 55-56 ; WO 2004/063195 A1

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185039-48-9 structure

185039-48-9

Literature: Klutchko, Sylvester R.; Hamby, James M.; Boschelli, Diane H.; Wu, Zhipei; Kraker, Alan J.; Amar, Aneesa M.; Hartl, Brian G.; Shen, Cynthia; Klohs, Wayne D.; Steinkampf, Randall W.; Driscoll, Denise L.; Nelson, James M.; Elliott, William L.; Roberts, Billy J.; Stoner, Chad L.; Vincent, Patrick W.; Dykes, Donald J.; Panek, Robert L.; Lu, Gina H.; Major, Terry C.; Dahring, Tawny K.; Hallak, Hussein; Bradford, Laura A.; Showalter, H. D. Hollis; Doherty, Annette M. Journal of Medicinal Chemistry, 1998 , vol. 41, # 17 p. 3276 - 3292

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185039-48-9 structure

185039-48-9

Literature: Klutchko, Sylvester R.; Hamby, James M.; Boschelli, Diane H.; Wu, Zhipei; Kraker, Alan J.; Amar, Aneesa M.; Hartl, Brian G.; Shen, Cynthia; Klohs, Wayne D.; Steinkampf, Randall W.; Driscoll, Denise L.; Nelson, James M.; Elliott, William L.; Roberts, Billy J.; Stoner, Chad L.; Vincent, Patrick W.; Dykes, Donald J.; Panek, Robert L.; Lu, Gina H.; Major, Terry C.; Dahring, Tawny K.; Hallak, Hussein; Bradford, Laura A.; Showalter, H. D. Hollis; Doherty, Annette M. Journal of Medicinal Chemistry, 1998 , vol. 41, # 17 p. 3276 - 3292

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185039-48-9 structure

185039-48-9

Literature: Klutchko, Sylvester R.; Hamby, James M.; Boschelli, Diane H.; Wu, Zhipei; Kraker, Alan J.; Amar, Aneesa M.; Hartl, Brian G.; Shen, Cynthia; Klohs, Wayne D.; Steinkampf, Randall W.; Driscoll, Denise L.; Nelson, James M.; Elliott, William L.; Roberts, Billy J.; Stoner, Chad L.; Vincent, Patrick W.; Dykes, Donald J.; Panek, Robert L.; Lu, Gina H.; Major, Terry C.; Dahring, Tawny K.; Hallak, Hussein; Bradford, Laura A.; Showalter, H. D. Hollis; Doherty, Annette M. Journal of Medicinal Chemistry, 1998 , vol. 41, # 17 p. 3276 - 3292

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185039-48-9 structure

185039-48-9

Literature: Klutchko, Sylvester R.; Hamby, James M.; Boschelli, Diane H.; Wu, Zhipei; Kraker, Alan J.; Amar, Aneesa M.; Hartl, Brian G.; Shen, Cynthia; Klohs, Wayne D.; Steinkampf, Randall W.; Driscoll, Denise L.; Nelson, James M.; Elliott, William L.; Roberts, Billy J.; Stoner, Chad L.; Vincent, Patrick W.; Dykes, Donald J.; Panek, Robert L.; Lu, Gina H.; Major, Terry C.; Dahring, Tawny K.; Hallak, Hussein; Bradford, Laura A.; Showalter, H. D. Hollis; Doherty, Annette M. Journal of Medicinal Chemistry, 1998 , vol. 41, # 17 p. 3276 - 3292

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185039-48-9 structure

185039-48-9

Literature: Klutchko, Sylvester R.; Hamby, James M.; Boschelli, Diane H.; Wu, Zhipei; Kraker, Alan J.; Amar, Aneesa M.; Hartl, Brian G.; Shen, Cynthia; Klohs, Wayne D.; Steinkampf, Randall W.; Driscoll, Denise L.; Nelson, James M.; Elliott, William L.; Roberts, Billy J.; Stoner, Chad L.; Vincent, Patrick W.; Dykes, Donald J.; Panek, Robert L.; Lu, Gina H.; Major, Terry C.; Dahring, Tawny K.; Hallak, Hussein; Bradford, Laura A.; Showalter, H. D. Hollis; Doherty, Annette M. Journal of Medicinal Chemistry, 1998 , vol. 41, # 17 p. 3276 - 3292

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185039-48-9 structure

185039-48-9

Literature: Klutchko, Sylvester R.; Hamby, James M.; Boschelli, Diane H.; Wu, Zhipei; Kraker, Alan J.; Amar, Aneesa M.; Hartl, Brian G.; Shen, Cynthia; Klohs, Wayne D.; Steinkampf, Randall W.; Driscoll, Denise L.; Nelson, James M.; Elliott, William L.; Roberts, Billy J.; Stoner, Chad L.; Vincent, Patrick W.; Dykes, Donald J.; Panek, Robert L.; Lu, Gina H.; Major, Terry C.; Dahring, Tawny K.; Hallak, Hussein; Bradford, Laura A.; Showalter, H. D. Hollis; Doherty, Annette M. Journal of Medicinal Chemistry, 1998 , vol. 41, # 17 p. 3276 - 3292

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185039-48-9 structure

185039-48-9

Literature: Palmer, Brian D.; Smaill, Jeff B.; Rewcastle, Gordon W.; Dobrusin, Ellen M.; Kraker, Alan; Moore, Charles W.; Steinkampf, Randall W.; Denny, William A. Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 7 p. 1931 - 1935