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6616-56-4

6616-56-4 structure
6616-56-4 structure
  • Name: MSX-127
  • Chemical Name: 2,5-Dihydroxy-1,4-bis-(morpholinomethyl)-benzol
  • CAS Number: 6616-56-4
  • Molecular Formula: C16H24N2O4
  • Molecular Weight: 308.37300
  • Catalog: Signaling Pathways GPCR/G Protein CXCR
  • Create Date: 2016-03-23 18:59:25
  • Modify Date: 2024-02-04 17:46:35
  • MSX-127 is a CXCR4 antagonist. MSX-127 inhibits cancer metastasis[1].

Name 2,5-Dihydroxy-1,4-bis-(morpholinomethyl)-benzol
Synonyms 1,4-diacetoxy-2,5-bis-morpholin-4-ylmethyl-benzene
Methyl 1H-benzo[d]iMidazole-2-carboxylate
2,5-bis-morpholin-4-ylmethyl-benzene-1,4-diol
2-(phenoxy)ethanamide
2,5-Bis-morpholinomethyl-hydrochinon-diacetat
2,5-bis-(morpholinomethyl)-hydroquinone
1,4-Benzenediol,2,5-bis(4-MorpholinylMethyl)-,1,4-diacetate
2,5-Bis-<morpholinomethyl>-hydrochinon
MSX-127
Description MSX-127 is a CXCR4 antagonist. MSX-127 inhibits cancer metastasis[1].
Related Catalog
Target

CXCR4

In Vitro The C-X-C chemokine receptor-4 (CXCR4) is a seven trans-membrane G-protein coupled receptor (GPCR) classified as a member of the family I GPCR or rhodopsin-like GPCR family. CXCR4 plays an important role in cancer metastasis, regulation of stem cell trafficking, and neovascularization[1].
References

[1]. Zhan W, et al. Discovery of small molecule CXCR4 antagonists. J Med Chem. 2007 Nov 15;50(23):5655-64.

Density 1.278g/cm3
Boiling Point 486.7ºC at 760 mmHg
Molecular Formula C16H24N2O4
Molecular Weight 308.37300
Flash Point 248.2ºC
Exact Mass 308.17400
PSA 65.40000
LogP 0.63800
Index of Refraction 1.605