CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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MB8480000
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CHEMICAL NAME :
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Glycine, N,N-bis(2-chloroethyl)-, hydrochloride
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CAS REGISTRY NUMBER :
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2619-97-8
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LAST UPDATED :
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199203
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DATA ITEMS CITED :
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4
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MOLECULAR FORMULA :
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C6-H11-Cl2-N-O2.Cl-H
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MOLECULAR WEIGHT :
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236.54
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WISWESSER LINE NOTATION :
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QV1N2G2G &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intracerebral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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113 ug/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 18,760,1966
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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15 mg/kg
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TOXIC EFFECTS :
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Tumorigenic - active as anti-cancer agent
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REFERENCE :
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PHBUA9 Pharmaceutical Bulletin. (Tokyo, Japan) V.1-5, 1953-57. For publisher information, see CPBTAL. Volume(issue)/page/year: 2,275,1954
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Mammal - dog
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DOSE/DURATION :
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1 mg/kg
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TOXIC EFFECTS :
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Gastrointestinal - other changes Blood - leukopenia Blood - other changes
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REFERENCE :
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CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Primate - monkey
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DOSE/DURATION :
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1 mg/kg
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TOXIC EFFECTS :
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Blood - leukopenia Blood - other changes
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REFERENCE :
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CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965
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