352431-24-4

352431-24-4 structure
352431-24-4 structure
  • Name: Glyceryl Tri(octanoate-d15)
  • Chemical Name: glyceryl tri(octanoate-d15)
  • CAS Number: 352431-24-4
  • Molecular Formula: C27H5D45O6
  • Molecular Weight: 515.96
  • Create Date: 2018-03-10 08:00:00
  • Modify Date: 2024-01-05 10:10:16
  • Tricaprilin-d15 is the deuterium labeled Tricaprilin. Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer's disease and has a role as an anticonvulsant and a plant metabolite[1][2].

Name glyceryl tri(octanoate-d15)
Synonyms Glyceryl Tri(octanoate-d15)
Propane-1,2,3-triyl tri(H)octanoate
1,2,3-Propanetriyl tri(H)octanoate
Octanoic-d acid, 1,2,3-propanetriyl ester
Description Tricaprilin-d15 is the deuterium labeled Tricaprilin. Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer's disease and has a role as an anticonvulsant and a plant metabolite[1][2].
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Tricaprylin

[3]. Kwok MK, et al. Re-thinking Alzheimer's disease therapeutic targets using gene-based tests. EBioMedicine. 2018 Nov;37:461-470.

Density 1.0±0.1 g/cm3
Boiling Point 508.0±17.0 °C at 760 mmHg
Molecular Formula C27H5D45O6
Molecular Weight 515.96
Flash Point 209.3±21.0 °C
Exact Mass 515.643188
PSA 78.90000
LogP 9.33
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.458