352438-80-3

352438-80-3 structure
352438-80-3 structure
  • Name: 3-(4-Isopropylphenyl)-1-methyl-1-(2H3)methylurea
  • Chemical Name: 1-methyl-3-(4-propan-2-ylphenyl)-1-(trideuteriomethyl)urea
  • CAS Number: 352438-80-3
  • Molecular Formula: C12H15D3N2O
  • Molecular Weight: 209.303
  • Catalog: Research Areas Others
  • Create Date: 2018-07-16 14:09:11
  • Modify Date: 2024-01-09 19:29:48
  • Isoproturon-d3 is the deuterium labeled Isoproturon[1]. Isoproturon belongs to the phenylurea herbicide family and is a systemic and selective herbicide. Isoproturon is widely applied for killing weeds in farmland, which can be used in the control of annual grasses and broad-leaved weeds in spring and winter wheat, winter rye and spring and winter barley[2][3].

Name 1-methyl-3-(4-propan-2-ylphenyl)-1-(trideuteriomethyl)urea
Synonyms Protugan-d3
Izoturon-d3
Graminon-d3
Harpun-d3
Arelon R-d3
Urea, N-methyl-N-methyl-d-N'-[4-(1-methylethyl)phenyl]-
3-(4-Isopropylphenyl)-1-methyl-1-(H)methylurea
Isoproturon-d3
Tolkan-d3
Alon-d3
Description Isoproturon-d3 is the deuterium labeled Isoproturon[1]. Isoproturon belongs to the phenylurea herbicide family and is a systemic and selective herbicide. Isoproturon is widely applied for killing weeds in farmland, which can be used in the control of annual grasses and broad-leaved weeds in spring and winter wheat, winter rye and spring and winter barley[2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Feng Fan Lu, et al. Isoproturon-Induced Salicylic Acid Confers Arabidopsis Resistance to Isoproturon Phytotoxicity and Degradation in Plants. J Agric Food Chem. 2018 Dec 19;66(50):13073-13083.  

[3]. Mian Muhammad, et al. Determination of Isoproturon in Environmental Samples Using the QuEChERS Extraction-Spectrofluorimetric Method. Environ Toxicol Chem. 2019 Dec38(12):2614-2620.  

Density 1.1±0.1 g/cm3
Boiling Point 353.2±25.0 °C at 760 mmHg
Melting Point 158ºC
Molecular Formula C12H15D3N2O
Molecular Weight 209.303
Flash Point 167.4±23.2 °C
Exact Mass 209.160736
PSA 32.34000
LogP 2.32
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.555