362049-51-2

362049-51-2 structure

Name: Methyl 4-hydroxy(2H4)benzoate
Chemical Name: methyl 2,3,5,6-tetradeuterio-4-hydroxybenzoate
CAS Number: 362049-51-2
Molecular Formula: C₈H₄D₄O₃
Molecular Weight: 156.172
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-09-04 16:54:11
Modify Date: 2024-01-12 09:18:21
Methyl paraben-d4 is the deuterium labeled Methyl Paraben[1]. Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, drugs and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity[2].

Name	methyl 2,3,5,6-tetradeuterio-4-hydroxybenzoate
Synonyms	Mekkings M-d4 methyl 4-hydroxybenzoate-2,3,5,6-d4 Paridol-d4 Preserval-d4 Metaben-d4 Metagin-d4 Methyl Paraben-d4 Solbrol-d4 Benzoic-2,3,5,6-d acid, 4-hydroxy-, methyl ester Maseptol-d4 Methyl 4-hydroxy(H)benzoate Killitol-d4 Danisol M-d4

Description	Methyl paraben-d4 is the deuterium labeled Methyl Paraben[1]. Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, drugs and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity[2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Soni MG, et al. Evaluation of the health aspects of methyl paraben: a review of the published literature. Food Chem Toxicol. 2002 Oct;40(10):1335-73.