Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: BUCINDOLOL
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70369-47-0

70369-47-0 structure

70369-47-0 structure

Name: BUCINDOLOL
Chemical Name: 2-[2-hydroxy-3-[[1-(1H-indol-3-yl)-2-methylpropan-2-yl]amino]propoxy]benzonitrile,hydrochloride
CAS Number: 70369-47-0
Molecular Formula: C₂₂H₂₅N₃O₂
Molecular Weight: 363.45300
Create Date: 2016-02-16 10:37:52
Modify Date: 2024-04-02 11:28:44

Name	2-[2-hydroxy-3-[[1-(1H-indol-3-yl)-2-methylpropan-2-yl]amino]propoxy]benzonitrile,hydrochloride
Synonyms	o-(2-Hydroxy-3-((2-indol-3-yl-1,1-dimethylethyl)amino)propoxy)benzonitrile monohydrochloride Bucindolol HCl Bucindolol hydrochloride Benzonitrile,2-(2-hydroxy-3-((2-(1H-indol-3-yl)-1,1-dimethylethyl)amino)propoxy)-,monohydrochloride 2-(2-Hydroxy-3-((2-(3-indolyl)-1,1-dimethylethyl)amino)propoxy)benzonitrile hydrochloride Bucindolol hydrochloride (USAN)

Boiling Point	605.3ºC at 760 mmHg
Molecular Formula	C₂₂H₂₅N₃O₂
Molecular Weight	363.45300
Flash Point	319.9ºC
Exact Mass	363.19500
PSA	81.07000
LogP	3.78108

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DI4605000

CHEMICAL NAME :: Benzonitrile, 2-(2-hydroxy-3-((2-(1H-indol-3-yl)-1,1-dimethylethyl) amino)propoxy)-, monohydrochloride

CAS REGISTRY NUMBER :: 70369-47-0

LAST UPDATED :: 198910

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C22-H25-N3-O2.Cl-H

MOLECULAR WEIGHT :: 399.96

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: NDADD8 New Drugs Annual: Cardiovascular Drugs. (New York, NY) V.1-2, 1983-84. For publisher information, see NCDREP. Volume(issue)/page/year: 1,1,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: NDADD8 New Drugs Annual: Cardiovascular Drugs. (New York, NY) V.1-2, 1983-84. For publisher information, see NCDREP. Volume(issue)/page/year: 1,1,1983