141781-17-1
141781-17-1 structure
- Name: (2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine
- Chemical Name: 1-[(5R,6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione
- CAS Number: 141781-17-1
- Molecular Formula: C24H43N3O8SSi2
- Molecular Weight: 589.85000
- Create Date: 2017-08-10 21:28:34
- Modify Date: 2024-01-10 16:47:15
| Name | 1-[(5R,6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione |
|---|---|
| Synonyms |
Tsao-T
C24H43N3O8SSi2 2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)pyrimidine 2,4(1H,3H)-Pyrimidinedione,1-(4-amino-9-(((1,1-dimethylethyl)dimethylsilyl)oxy)-6-((((1,1-dimethylethyl)dimethylsilyl)oxy)methyl)-1,7-dioxa-2-thiaspiro(4,4)non-3-en-8-yl)-5-methyl-,S,S-dioxide. (5R-(5alpha,6beta,8beta,9alpha)) 3qo9 |
| Density | 1.22g/cm3 |
|---|---|
| Molecular Formula | C24H43N3O8SSi2 |
| Molecular Weight | 589.85000 |
| Exact Mass | 589.23100 |
| PSA | 160.58000 |
| LogP | 5.24690 |
| Index of Refraction | 1.541 |
|
~85%
141781-17-1 |
| Literature: Perez-Perez; San-Felix; Camarasa; Balzarini; De Clercq Tetrahedron Letters, 1992 , vol. 33, # 21 p. 3029 - 3032 |
|
~74%
141781-17-1 |
| Literature: Perez-Perez; San-Felix; Balzarini; De Clercq; Camarasa Journal of Medicinal Chemistry, 1992 , vol. 35, # 16 p. 2988 - 2995 |
|
~%
141781-17-1 |
| Literature: Perez-Perez; San-Felix; Camarasa; Balzarini; De Clercq Tetrahedron Letters, 1992 , vol. 33, # 21 p. 3029 - 3032 |
|
~%
141781-17-1 |
| Literature: Perez-Perez; San-Felix; Balzarini; De Clercq; Camarasa Journal of Medicinal Chemistry, 1992 , vol. 35, # 16 p. 2988 - 2995 |
|
~%
141781-17-1 |
| Literature: Perez-Perez; San-Felix; Balzarini; De Clercq; Camarasa Journal of Medicinal Chemistry, 1992 , vol. 35, # 16 p. 2988 - 2995 |
|
~%
141781-17-1 |
| Literature: Perez-Perez; San-Felix; Balzarini; De Clercq; Camarasa Journal of Medicinal Chemistry, 1992 , vol. 35, # 16 p. 2988 - 2995 |
|
~%
141781-17-1 |
| Literature: Perez-Perez; San-Felix; Balzarini; De Clercq; Camarasa Journal of Medicinal Chemistry, 1992 , vol. 35, # 16 p. 2988 - 2995 |
|
~%
141781-17-1 |
| Literature: Perez-Perez; San-Felix; Camarasa; Balzarini; De Clercq Tetrahedron Letters, 1992 , vol. 33, # 21 p. 3029 - 3032 |
| Precursor 5 | |
|---|---|
| DownStream 6 | |
![1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methyl-3-(3-methylbut-2-enyl)pyrimidine-2,4-dione structure](https://image.chemsrc.com/caspic/037/142102-82-7.png)
![1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-(hydroxymethyl)-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione structure](https://image.chemsrc.com/caspic/376/141684-47-1.png)
![1-[(6R,8R)-4-amino-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione structure](https://image.chemsrc.com/caspic/300/141684-49-3.png)
![4-amino-1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidin-2-one structure](https://image.chemsrc.com/caspic/044/142102-77-0.png)
![1-[(6R,8R,9R)-4-amino-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-9-hydroxy-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione structure](https://image.chemsrc.com/caspic/338/141684-48-2.png)
![1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-3-ethyl-5-methylpyrimidine-2,4-dione structure](https://image.chemsrc.com/caspic/113/142102-80-5.png)