476473-97-9
476473-97-9 structure
- Name: 5-(Chloromethyl)-2,2-difluorobenzo[d][1,3]dioxole
- Chemical Name: 5-(chloromethyl)-2,2-difluoro-1,3-benzodioxole
- CAS Number: 476473-97-9
- Molecular Formula: C8H5ClF2O2
- Molecular Weight: 206.57400
- Create Date: 2018-11-28 06:15:04
- Modify Date: 2024-01-06 05:16:55
| Name | 5-(chloromethyl)-2,2-difluoro-1,3-benzodioxole |
|---|---|
| Synonyms |
5-(CHLOROMETHYL)-2,2-DIFLUORO-2H-1,3-BENZODIOXOLE
5-chloromethyl-2,2-difluoro-1,3-benzodioxole 5-(chloromethyl)-2,2-difluorobenzo[d][1,3]dioxole 5-CHLOROMETHYL-2,2-DIFLUORO-BENZO[1,3]DIOXOLE |
| Molecular Formula | C8H5ClF2O2 |
|---|---|
| Molecular Weight | 206.57400 |
| Exact Mass | 205.99500 |
| PSA | 18.46000 |
| LogP | 2.74690 |
|
~99%
476473-97-9 |
| Literature: VERTEX PHARMACEUTICALS INCORPORATED Patent: WO2009/73757 A1, 2009 ; Location in patent: Page/Page column 20 ; |
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476473-97-9 |
| Literature: VERTEX PHARMACEUTICALS INCORPORATED Patent: US2012/46330 A1, 2012 ; US 20120046330 A1 |
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476473-97-9 |
| Literature: VERTEX PHARMACEUTICALS INCORPORATED; KESHAVARZ-SHOKRI, Ali; ZHANG, Beili; ALCACIO, Tim, Edward; LEE, Elaine, Chungmin; ZHANG, Yuegang; KRAWIEC, Mariusz Patent: WO2011/119984 A1, 2011 ; WO 2011/119984 A1 |
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476473-97-9 |
| Literature: Vertex Pharmaceuticals Incorported Patent: US2011/98311 A1, 2011 ; |
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476473-97-9 |
| Literature: Vertex Pharmaceuticals Incorported Patent: US2011/98311 A1, 2011 ; |
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476473-97-9 |
| Literature: DAINIPPON SUMITOMO PHARMA CO., LTD. Patent: US2012/225876 A1, 2012 ; |
| Precursor 6 | |
|---|---|
| DownStream 4 | |
![1-(2,2-Difluorobenzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid structure](https://image.chemsrc.com/caspic/189/862574-88-7.png)
![3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL)CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID HYDROCHLORIDE structure](https://image.chemsrc.com/caspic/433/1160221-26-0.png)
![1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile structure](https://image.chemsrc.com/caspic/227/862574-87-6.png)