148757-94-2

148757-94-2 structure

Name: AQC
Chemical Name: [3-(6-aminoquinolin-2-yl)-2,5-dioxopyrrolidin-1-yl]-oxidocarbamic acid
CAS Number: 148757-94-2
Molecular Formula: C₁₄H₁₁N₃O₄
Molecular Weight: 315.262
Catalog: Research Areas Others
Create Date: 2019-01-01 19:22:45
Modify Date: 2024-01-09 06:12:43
AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent used in for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels[1][2].

Name	[3-(6-aminoquinolin-2-yl)-2,5-dioxopyrrolidin-1-yl]-oxidocarbamic acid
Synonyms	AHC reagent {[3-(6-Amino-2-quinolinyl)-2,5-dioxo-1-pyrrolidinyl](carboxy)amino}oxidanide AccQ.Fluor Carbamato, N-[3-(6-amino-2-quinolinyl)-2,5-dioxo-1-pyrrolidinyl]-N-hydroxy-, ion(1-) Carbamic acid,N-6-quinolinyl-,2,5-dioxo-1-pyrrolidinyl ester 6-Aminoquinolyl-N-hydroxysuccinimidylcarbamate

Description	AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent used in for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	The use of AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate), which reacts with primary and secondary amino acids to yield fluorescent derivates (λ excitation and emission at 250 and 395 nm, respectively), allowing amino acid detection at under-picomolar levels, overcomes many of the drawbacks associated with the rest of derivatising reagents[1][2].
References	[1]. Bosch L, et al. Application of the 6-aminoquinolyl-N-hydroxysccinimidyl carbamate (AQC) reagent to the RP-HPLC determination of amino acids in infant foods. J Chromatogr B Analyt Technol Biomed Life Sci. 2006;831(1-2):176-183. [2]. Cohen SA, et al. Applications of amino acid derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate. Analysis of feed grains, intravenous solutions and glycoproteins. J Chromatogr A. 1994;661(1-2):25-34.