166981-13-1

166981-13-1 structure

Name: CT-2584
Chemical Name: 1-[11-(dodecylamino)-10-hydroxyundecyl]-3,7-dimethylpurine-2,6-dione
CAS Number: 166981-13-1
Molecular Formula: C₃₀H₅₅N₅O₃
Molecular Weight: 533.79
Create Date: 2017-09-14 11:48:58
Modify Date: 2024-01-18 19:46:43
CT-2584 is a chemotherapeutic compound that reduces the expression of NKEF-B in several tumor cell types and kills tumor cells by inducing the production of ROS in mitochondria, commonly used in cancer research[1].

Name	1-[11-(dodecylamino)-10-hydroxyundecyl]-3,7-dimethylpurine-2,6-dione
Synonyms	1-(11-(dodecylamino)-10-hydroxyundecyl)-3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione CT-2584 1-(11-Dodecylamino-10-hydroxylundecyl)-3,7-dimethylxanthine 1-(11-(dodecylamino)-10-hydroxyundecyl)-3,7-dimethylxanthine 1H-Purine-2,6-dione,1-(11-(dodecylamino)-10-hydroxyundecyl)-3,7-dihydro-3,7-dimethyl

Description	CT-2584 is a chemotherapeutic compound that reduces the expression of NKEF-B in several tumor cell types and kills tumor cells by inducing the production of ROS in mitochondria, commonly used in cancer research[1].
Related Catalog	Research Areas >> Cancer
In Vitro	CT-2584 (0-7 μM, 3 days) 对 ECV304 具有一定的毒性作用，而 B/1 细胞对此具有较强的抵抗力[1]。 Cell Viability Assay[1] Cell Line: ECV304 and its derived cell lines Concentration: 0-7 μM Incubation Time: 3 days Result: Inhibited ECV304 and B/1 cells with the LC50 value of 4.5 μ M and 6.5 μ M,respectively. After 7 μM treatment, the shape of ECV304 or ECV304/pCE2 cells became round and detached from the plate, while B/1 cells could clearly observe living cells that retained the spindle shape.
References	[1]. H Shau, et al. Endogenous natural killer enhancing factor-B increases cellular resistance to oxidative stresses. Free Radic Biol Med. 1997;22(3):497-507.