GL Biochem (Shanghai) Ltd.
China
Product Name: MeOSuc-Ala-Ala-Pro-Val-AMC
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Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: MEOSUC-ALA-ALA-PRO-VAL-AMC
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
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Zhejiang Hangyu API Co., Ltd
China
Product Name: MeOSuc-Ala-Ala-Pro-Val-AMC
Price: $Inquiry/1kg
Purity: 99.0%
Stocking Period: 1 Day
Contact: Vinnie

72252-90-5

72252-90-5 structure

72252-90-5 structure

Name: MeOSuc-AAPV-AMC
Chemical Name: meosuc-ala-ala-pro-val-amc
CAS Number: 72252-90-5
Molecular Formula: C₃₁H₄₁N₅O₉
Molecular Weight: 627.685
Catalog: Biochemical Amino acids and their derivatives Proline derivatives
Create Date: 2019-01-03 17:47:15
Modify Date: 2024-01-07 09:22:49
MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (Km: 362 μM, Ex=380 nm, Em=460 nm)[1].

Name	meosuc-ala-ala-pro-val-amc
Synonyms	MEOSUC-AAPV-AMC N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL 7-AMIDO-4-METHYL-COUMARIN MEOSUC-ALA-ALA-PRO-VAL-7-AMINO-4-METHYLCOUMARIN N-(4-Methoxy-4-oxobutanoyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-valinamide ELASTASE SUBSTRATE V,FLUOROGENIC N-methoxysuccinyl-Ala-Ala-Pro-Val-7-amidomethylcoumarin L-Valinamide, N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- MFCD00077135 N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL 7-*AMI DO-4-METHYL methoxy-succinyl-alanyl-alanyl-prolyl-valine-7-amino-4-methylcoumarin ELASTASE SUBSTRATE V

Description	MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (Km: 362 μM, Ex=380 nm, Em=460 nm)[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	Elastase[1]
In Vitro	Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs)[1]. 1. Prepare The stock solutions of fluorogenic peptide substrates and stored at -40 °C. 2. Dilute the stock solution∼100-fold into reaction buffers to prepare 2× substrate buffers (400 μM). 3. The enzymes are then incubated for 40 min. 4. The enzymatic activity is subsequently assayed by rapidly mixing 50 μL of the substrate buffer with 50 μL of the enzyme solution in a 96-well clear bottom plates. 5. Record the fluorescence change on a FLEXStation fluorescence plate reader.
References	[1]. Dmitri Ivanov, et al. A serpin from the gut bacterium Bifidobacterium longum inhibits eukaryotic elastase-like serine proteases. J Biol Chem. 2006 Jun 23;281(25):17246-17252.

Density	1.3±0.1 g/cm3
Boiling Point	983.7±65.0 °C at 760 mmHg
Molecular Formula	C₃₁H₄₁N₅O₉
Molecular Weight	627.685
Flash Point	548.7±34.3 °C
Exact Mass	627.290405
PSA	193.22000
LogP	1.99
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.570
Storage condition	−20°C
Water Solubility	Soluble in DMSO

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3