136661-76-2

136661-76-2 structure

Name: Defensin HNP-3 (human) trifluoroacetate salt
Chemical Name: α-DEFENSIN-3 (HUMAN)
CAS Number: 136661-76-2
Molecular Formula: C₁₅₁H₂₂₂N₄₄O₄₀S₆
Molecular Weight: 3486.04
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2019-02-04 06:00:45
Modify Date: 2024-01-12 21:22:45
Defensin HNP-3 human is a cytotoxic antibiotic peptide known as "defensin". Defensin HNP-3 human has inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Defensin HNP-3 human is initially synthesized as the 94 amino acids preproHNP(1-94), which is hydrolyzed to proHNP(20-94) and converted to mature HNP(65-94) after the removal of anion precursors[1][2].

Name	α-DEFENSIN-3 (HUMAN)
Synonyms	Defensin HNP-3 (human)

Description	Defensin HNP-3 human is a cytotoxic antibiotic peptide known as "defensin". Defensin HNP-3 human has inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Defensin HNP-3 human is initially synthesized as the 94 amino acids preproHNP(1-94), which is hydrolyzed to proHNP(20-94) and converted to mature HNP(65-94) after the removal of anion precursors[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Valore EV, et al. Intramolecular inhibition of human defensin HNP-1 by its propiece. J Clin Invest. 1996 Apr 1;97(7):1624-9. [2]. Ganz T, et al. Defensins. Natural peptide antibiotics of human neutrophils[J]. The Journal of clinical investigation, 1985, 76(4): 1427-1435.