Name | 3-[(2,2,2-trifluoroacetyl)amino]propanoyl chloride |
---|---|
Synonyms | Propanoyl chloride,3-[(trifluoroacetyl)amino] |
Description | N-trifluoroacetyl-β-alanyl chloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
---|---|
Related Catalog | |
Target |
Cleavable |
In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. |
References |
Molecular Formula | C5H5ClF3NO2 |
---|---|
Molecular Weight | 203.54700 |
Exact Mass | 202.99600 |
PSA | 49.66000 |
LogP | 1.66070 |
~98% 87639-76-7 |
Literature: Gani, David; Young, Douglas W. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1355 - 1362 |
Precursor 1 | |
---|---|
DownStream 2 | |