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91842-53-4

91842-53-4 structure
91842-53-4 structure
  • Name: Benzyl-PEG2-CH2COOH
  • Chemical Name: {2-[2-(Benzyloxy)ethoxy]ethoxy}acetic acid
  • CAS Number: 91842-53-4
  • Molecular Formula: C13H18O5
  • Molecular Weight: 254.279
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-05-20 06:32:35
  • Modify Date: 2024-01-07 10:40:47
  • Benzyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name {2-[2-(Benzyloxy)ethoxy]ethoxy}acetic acid
Synonyms Acetic acid, 2-[2-[2-(phenylmethoxy)ethoxy]ethoxy]-
10-phenyl-3,6,9-trioxadecanoic acid
{2-[2-(Benzyloxy)ethoxy]ethoxy}acetic acid
2-(2-(2-(Benzyloxy)ethoxy)ethoxy)acetic acid
Description Benzyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Boiling Point 409.7±30.0 °C at 760 mmHg
Molecular Formula C13H18O5
Molecular Weight 254.279
Flash Point 152.5±18.1 °C
Exact Mass 254.115417
PSA 64.99000
LogP 0.68
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.514