478801-48-8
478801-48-8 structure
- Name: N3-C4-NHS ester
- Chemical Name: (2,5-dioxopyrrolidin-1-yl) 5-azidopentanoate
- CAS Number: 478801-48-8
- Molecular Formula: C9H12N4O4
- Molecular Weight: 240.21600
- Catalog: Research Areas Cancer
- Create Date: 2017-06-02 01:22:13
- Modify Date: 2025-09-18 17:22:44
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N3-C4-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Name | (2,5-dioxopyrrolidin-1-yl) 5-azidopentanoate |
|---|---|
| Synonyms |
succinimidyl azidovalerate
succinimidyl 5-azidovalerate 1-succinimidyl 5-azidopentanoate 5-azidopentanoic acid N-hydroxysuccinimide ester 5-azidovaleric acid N-succinimidyl ester succinimidyl 5-azidopentanoate |
| Description | N3-C4-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
|---|---|
| Related Catalog | |
| Target |
Noncleavable |
| References |
| Molecular Formula | C9H12N4O4 |
|---|---|
| Molecular Weight | 240.21600 |
| Exact Mass | 240.08600 |
| PSA | 113.43000 |
| LogP | 0.46486 |
|
~87%
478801-48-8 |
| Literature: Seo, Tae Seok; Li, Zengmin; Ruparel, Hameer; Ju, Jingyue Journal of Organic Chemistry, 2003 , vol. 68, # 2 p. 609 - 612 |
|
~%
478801-48-8 |
| Literature: Seo, Tae Seok; Li, Zengmin; Ruparel, Hameer; Ju, Jingyue Journal of Organic Chemistry, 2003 , vol. 68, # 2 p. 609 - 612 |
|
~%
478801-48-8 |
| Literature: Seo, Tae Seok; Li, Zengmin; Ruparel, Hameer; Ju, Jingyue Journal of Organic Chemistry, 2003 , vol. 68, # 2 p. 609 - 612 |
|
~%
478801-48-8 |
| Literature: Brown, Sarah D.; Graham, Duncan Tetrahedron Letters, 2010 , vol. 51, # 38 p. 5032 - 5034 |
| Precursor 4 | |
|---|---|
| DownStream 0 | |