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778596-26-2

778596-26-2 structure
778596-26-2 structure
  • Name: HO-PEG10-CH2CH2COO<sup>t</sup>Bu
  • Chemical Name: tert-butyl 1-hydroxy-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oate
  • CAS Number: 778596-26-2
  • Molecular Formula: C27H54O13
  • Molecular Weight: 586.71000
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2017-11-20 00:57:10
  • Modify Date: 2025-08-25 21:27:42
  • Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024)[1]. Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel (HY-B0015) or docetaxel (HY-B0011)[2].

Name tert-butyl 1-hydroxy-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oate
Synonyms HO-PEG10-CH2CH2COOtBu
Description Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024)[1]. Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel (HY-B0015) or docetaxel (HY-B0011)[2].
Related Catalog
In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Huli, et al. A kind of preparation method of hydroxyl polyethylene glycol propionic ester. Patent

[2]. Miller ML, et al. Synthesis of taxoids with improved cytotoxicity and solubility for use in tumor-specific delivery.J Med Chem. 2004 Sep 23;47(20):4802-5.

Molecular Formula C27H54O13
Molecular Weight 586.71000
Exact Mass 586.35600
PSA 138.83000
LogP 0.87650
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