205989-12-4

205989-12-4 structure

Name: Luotonin A
Chemical Name: luotonin A
CAS Number: 205989-12-4
Molecular Formula: C₁₈H₁₁N₃O
Molecular Weight: 285.30
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2016-05-19 06:47:09
Modify Date: 2025-08-20 22:14:07
Luotonin A is an antiviral and antiphytopathogenic fungus agent. Luotonin A has good antiviral activity against tobacco mosaic virus (TMV). Luotonin A also has certain inhibitory activity on topoisomerase I and topoisomerase II. Luotonin A shows antitumor activity[1][2].

Name	luotonin A
Synonyms	Quino[2',3':3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one 3,2'-monomethylene-2-(quinol-2-yl)-4(3H)-quinazolinone LUOTONIN A 11,13-dihydroquino[2',3':3,4]pyrrolo[2,1-b]quinazolin-11-one Luotonine A luotonin Quinolino[2',3':3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one

Description	Luotonin A is an antiviral and antiphytopathogenic fungus agent. Luotonin A has good antiviral activity against tobacco mosaic virus (TMV). Luotonin A also has certain inhibitory activity on topoisomerase I and topoisomerase II. Luotonin A shows antitumor activity[1][2].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Hao Y, et al. Luotonin A and Its Derivatives as Novel Antiviral and Antiphytopathogenic Fungus Agents. J Agric Food Chem. 2020 Aug 19;68(33):8764-8773. [2]. Cagir A, et al. A naturally occurring human DNA topoisomerase I poison. J Am Chem Soc. 2003 Nov 12;125(45):13628-9.