61210-21-7

61210-21-7 structure

Name: 7-cyano-7-deazaguanosine
Chemical Name: 2-amino-5-cyano-3,4-dihydro-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-one
CAS Number: 61210-21-7
Molecular Formula: C₁₂H₁₃N₅O₅
Molecular Weight: 307.26
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-08-30 06:51:41
Modify Date: 2024-01-03 23:26:22
7-Cyano-7-deazaguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-amino-5-cyano-3,4-dihydro-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-one
Synonyms	PreQ0 2-amino-4-oxo-7-β-D-ribofuranosyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 2-amino-5-cyano-3,4-dihydro-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-4-one 2-amino-3,4-dihydro-4-oxo-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-5-carbonitrile 2-amino-5-cyano-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidin-4-one 2-amino-5-cyano-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]-pyrimidin-4-one

Description	7-Cyano-7-deazaguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Precursor 0
DownStream 1
81645-08-1