67605-85-0

67605-85-0 structure

Name: N-Butanoyl-L-homoserine lactone
Chemical Name: N-[(3S)-2-oxooxolan-3-yl]butanamide
CAS Number: 67605-85-0
Molecular Formula: C₈H₁₃NO₃
Molecular Weight: 171.194
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-10-15 18:24:23
Modify Date: 2025-08-25 11:00:32
N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm[1].

Name	N-[(3S)-2-oxooxolan-3-yl]butanamide
Synonyms	C4-homoserine lactone Butanamide, N-[(3S)-tetrahydro-2-oxo-3-furanyl]- N-Butyryl-DL-homoserin-lacton HL4 N-Butyryl-L-homoserine lactone N-[(3S)-2-oxotetrahydrofuran-3-yl]butanamide (+)-a(S)-butyr-amido-r-butyrolactone N-[(3S)-2-Oxotetrahydro-3-furanyl]butanamide butanoyl homoserine lactone

Description	N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Signaling Pathways >> Anti-infection >> Bacterial
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. Keith Alan Charlton, et al. Methods for the Treatment of an Infectious Bacterial Disease with an Anti-Lactone or Lactone Derived Signal Molecules Antibody. US20130045208A1

6305-38-0

67605-85-0

Literature: Nippon Kagaku Zasshi, , vol. 79, p. 81,83 Chem.Abstr., , p. 5448

Precursor 1
6305-38-0
DownStream 0