4330-34-1

4330-34-1 structure

Name: methyl 2-deoxy-3,5-di-o-p-toluoyl-d-*rib ofuranoside
Chemical Name: 2-hydroxy-2-[(2R,3S)-3-hydroxy-5-methoxy-3-(2-methylbenzoyl)oxolan-2-yl]-1-(2-methylphenyl)ethanone
CAS Number: 4330-34-1
Molecular Formula: C₂₂H₂₄O₆
Molecular Weight: 384.42
Catalog: Biochemical Carbohydrate Monosaccharide
Create Date: 2018-12-30 13:23:30
Modify Date: 2024-01-10 23:44:49
Methyl 2-deoxy-3,5-di-O-toluoyl-D-ribofuranoside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-hydroxy-2-[(2R,3S)-3-hydroxy-5-methoxy-3-(2-methylbenzoyl)oxolan-2-yl]-1-(2-methylphenyl)ethanone
Synonyms	methyl 2-deoxy-3,5-di-O-p-toluoyl-D-ribofuranoside 1-o-methyl-2-deoxy-3,5-di(p-toluoyl)-erythro-pentafuranose 2-deoxy-1-O-methyl-3,5-di-O-p-toluoyl-D-ribofuranose Methyl 2-Deoxy-3,5-di-O-p-toluoyl-D-erythro-pentoside Methyl (5ξ)-2-deoxy-3-C-(2-methylbenzoyl)-6-(2-methylphenyl)-D-erythro-hexodialdo-1,4-furanoside Methyl 2-deoxy-3,5-di-O-toluoyl-D-ribofuranoside D-erythro-Hexodialdo-1,4-furanoside, methyl 2-deoxy-3-C-(2-methylbenzoyl)-6-(2-methylphenyl)-, (5ξ)-

Description	Methyl 2-deoxy-3,5-di-O-toluoyl-D-ribofuranoside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.3±0.1 g/cm3
Boiling Point	581.4±50.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₄O₆
Molecular Weight	384.42
Flash Point	202.4±23.6 °C
Exact Mass	384.157288
PSA	93.06000
LogP	3.80
Vapour Pressure	0.0±1.7 mmHg at 25°C
Index of Refraction	1.607
Storage condition	−20°C

WGK Germany	3
HS Code	29389090

452-51-7

4330-34-1

Literature: Koegler, Martin; Busson, Roger; De Jonghe, Steven; Rozenski, Jef; Van Belle, Kristien; Louat, Thierry; Munier-Lehmann, Helne; Herdewijn, Piet Chemistry and Biodiversity, 2012 , vol. 9, # 3 p. 536 - 556

874-60-2

4330-34-1

Literature: Dhimitruka, Ilirian; SantaLucia Jr., John Synlett, 2004 , # 2 p. 335 - 337

22900-10-3

4330-34-1

Literature: Rolland, Valerie; Kotera, Mitsuharu; Lhomme, Jean Synthetic Communications, 1997 , vol. 27, # 20 p. 3505 - 3511

Precursor 2
452-51-7 874-60-2
DownStream 7
4330-21-6 29900-44-5 29900-45-6 108-28-1
91713-25-6 4449-38-1 4449-37-0

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