117857-95-1
117857-95-1 structure
- Name: L-CCG-IV
- Chemical Name: (1S,2R)-2-[(S)-amino(carboxy)methyl]cyclopropane-1-carboxylic acid
- CAS Number: 117857-95-1
- Molecular Formula: C6H9NO4
- Molecular Weight: 159.14000
- Catalog: Biochemical Amino acids and their derivatives Glycine derivatives
- Create Date: 2019-01-15 10:45:20
- Modify Date: 2024-01-05 22:10:01
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cis-α-(Carboxycyclopropyl)glycine (L-CCG III) is a potent, competitive glutamate uptake inhibitor. cis-α-(Carboxycyclopropyl)glycine is a substrate of glutamate transporters (GluT) (EC50: 13 μM, 2 μM for EAAT 1 and EAAT 2, respectively). cis-α-(Carboxycyclopropyl)glycine inhibits a Na+-dependent high-affinity L-glutamate uptake in glial plasmalemmal vesicles (GPV) and synaptosomes[1][2].
| Name | (1S,2R)-2-[(S)-amino(carboxy)methyl]cyclopropane-1-carboxylic acid |
|---|---|
| Synonyms |
MFCD00210186
l-ccg-iv |
| Description | cis-α-(Carboxycyclopropyl)glycine (L-CCG III) is a potent, competitive glutamate uptake inhibitor. cis-α-(Carboxycyclopropyl)glycine is a substrate of glutamate transporters (GluT) (EC50: 13 μM, 2 μM for EAAT 1 and EAAT 2, respectively). cis-α-(Carboxycyclopropyl)glycine inhibits a Na+-dependent high-affinity L-glutamate uptake in glial plasmalemmal vesicles (GPV) and synaptosomes[1][2]. |
|---|---|
| Related Catalog | |
| Target |
glutamate transporters (GluT)[1] |
| References |
| Molecular Formula | C6H9NO4 |
|---|---|
| Molecular Weight | 159.14000 |
| Exact Mass | 159.05300 |
| PSA | 100.62000 |
| Appearance | solid | off-white |
| Storage condition | Store at RT |
| Water Solubility | H2O: soluble |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |