150527-23-4

150527-23-4 structure

Name: FG-5893
Chemical Name: methyl 2-[4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl]pyridine-3-carboxylate
CAS Number: 150527-23-4
Molecular Formula: C₂₇H₂₉F₂N₃O₂
Molecular Weight: 465.53500
Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
Create Date: 2017-03-12 07:55:18
Modify Date: 2024-04-08 16:09:36
FG-5893 is a 5-HT1A receptor agonist and a 5-HT2 receptor antagonist. FG-5893 has anxiolytic effect[1][2].

Name	methyl 2-[4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl]pyridine-3-carboxylate
Synonyms	fg-5893

Description	FG-5893 is a 5-HT1A receptor agonist and a 5-HT2 receptor antagonist. FG-5893 has anxiolytic effect[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. Gunnar Andersson, et al. Effects of FG 5893, a new compound with 5-HT1A receptor agonistic and 5-HT2 receptor antagonistic properties, on male rat sexual behavior. European Journal of Pharmacology. Volume 255, Issues 1–3, 1 April 1994, Pages 131-137. [2]. Albinsson A, et al. Preclinical pharmacology of FG5893: a potential anxiolytic drug with high affinity for both 5-HT1A and 5-HT2A receptors. Eur J Pharmacol. 1994 Aug 22;261(3):285-94.