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31690-09-2

31690-09-2 structure
31690-09-2 structure
  • Name: Levomefolic acid
  • Chemical Name: (S)-2-(4-((((S)-2-Amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid
  • CAS Number: 31690-09-2
  • Molecular Formula: C20H25N7O6
  • Molecular Weight: 459.456
  • Catalog: API Vitamins and minerals Vitamin C drugs
  • Create Date: 2018-08-11 11:42:53
  • Modify Date: 2026-07-16 15:13:41
  • Levomefolic acid (5-MTHF) is the natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. IC50 value: Target: Folate analogLevomefolic acid has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers. Levomefolic acid (5-MTHF) has the prominent antioxidant activity. A high dose of 5-MTHF or folic acid does not influence Natural killer (NK) cell function in vitro.

Name (S)-2-(4-((((S)-2-Amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid
Synonyms N-[4-[[[(6S)-2-Amino-5-methyl-1,4,5,6,7,8-hexahydro-4-oxopteridine-6-yl]methyl]amino]benzoyl]-L-glutamic acid
Levomefolic Acid //BP
L(-)-5-Methyl-5,6,7,8-tetrahydrofolic acid
(S)-2-(4-((((S)-2-Amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioicaci
(S)-2-(4-((((S)-2-Amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pen
8S95DH25XC
5-Methyl-(6S)-tetrahydrofolic acid
5-Methyltetrahydrofolate
L-Glutamic acid, N-(4-(((2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-, (S)
N-[4-[[[[(6S)-2-Amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxopteridin]-6-yl]methyl]amino]benzoyl]-L-glutamic acid
Levomefolic Acid (See also L375720)
N-[4-({[(6S)-2-Amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
L-Methyl Tetra Folate
l-N5
Levomefolate (5-methyl-tetrahydrofolic acid)
L-methyl acid
(S)-2-[4-[[[(S)-2-Amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl]amino]benzamido]pentanedioic Acid
5-methyltetrahydrofolic acid
L-5-Methyltetrahydrofola acide
Levomefolic Acid D3Q: What is Levomefolic Acid D3 Q: What is the CAS Number of Levomefolic Acid D3 Q: What is the storage condition of Levomefolic Acid D3 Q: What e the applications of Levomefolic Acid D3
(S)-2-(4-((((S)-2-Amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzami
N-[4-[[((6S)-2-Amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid
N-(5-methyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
L-5-Methyltetrahydrofolic acid
lL-5-Methyltetrahydrofolic acid
Unii-8S95dh25xc
(6S)-5-Methyltetrahydrofolic Acid in DMSO:H2O=1:1
N-[4-({[(6S)-2-Amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl]methyl}amino)benzoyl]-L-glutamic acid
(S)-2-(4-((((S)-2-Amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)
8-pentamethoxyflavone
L-5-methyltetrahydrofolic acid
(6S)-5-Methyltetrahydrofolic acid
5lLCH3-folateH4
L-5-Methyltetrahydrofolate
LevoMefolic Acid (See also L375720)
Methyl-L-tetrahydrofolic A
5-MTHF
N-[4-[[[(6S)-2-Amino-3,4,5,6,7,8-hexahydro-5-Methyl-4-oxo-6-pteridinyl]Methyl]amino]benzoyl]-L-glutaMic Acid
5-Methyltetrahydrofolic Acid-[13C,d3] in DMSO:H2O=1:1
levomefolinic acid
5-Methyl-(6S)-tetrahydrofolic Acid
(2S)-2-{[4-({[(6S)-2-Amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl]methyl}amino)benzoyl]amino}pentanedioic acid
(S)-N-[4-[[(2-Amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
L-Glutamic acid, N-[4-[[[(6S)-2-amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]
Description Levomefolic acid (5-MTHF) is the natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. IC50 value: Target: Folate analogLevomefolic acid has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers. Levomefolic acid (5-MTHF) has the prominent antioxidant activity. A high dose of 5-MTHF or folic acid does not influence Natural killer (NK) cell function in vitro.
Related Catalog
References

[1]. Hirsch S, Miranda D, Mu?oz E, et al. Natural killer cell cytotoxicity is not regulated by folic acid in vitro. Nutrition. 2013 Jan 9. pii: S0899-9007(12)00404-2.

[2]. Liu Y, Green TJ, Wong P, Kitts DD. Microencapsulation of L-5-methyltetrahydrofolic Acid with ascorbate improves stability in baked bread products. J Agric Food Chem. 2013 Jan 9;61(1):247-54.

[3]. Merola N, Alonso FJ, Ros G, Castón MJ. Antioxidant activity comparison between [6S]-5-methyltetrahydrofolic acid calcium salt and the related racemate form. Food Chem. 2013 Jan 15;136(2):984-8.

[4]. Liu Y, Tomiuk S, Rozoy E, et al. Thermal oxidation studies on reduced folate, L-5-methyltetrahydrofolic acid (L-5-MTHF) and strategies for stabilization using food matrices. J Food Sci. 2012 Feb;77(2):C236-43.

[5]. Bashir M Rezka, Guido R.M.M Haenena, Wim J.F van der Vijgha, et al. Tetrahydrofolate and 5-methyltetrahydrofolate are folates with high antioxidant activity. Identification of the antioxidant pharmacophore. 2003,555(3):601-605.

[6]. Levomefolic acid

Density 1.6±0.1 g/cm3
Molecular Formula C20H25N7O6
Molecular Weight 459.456
Exact Mass 459.186646
PSA 202.77000
LogP -2.61
Index of Refraction 1.733

~%

31690-09-2 structure

31690-09-2

Literature: WO2013/25203 A1, ;
Precursor  1

DownStream  0

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