Name | 2-[4-[4-(4-benzhydryloxypiperidin-1-yl)butanoyl]phenyl]-2-methylpropanoic acid |
---|---|
Synonyms |
p-(4-(4-(Diphenylmethoxy)piperidino)butyryl)-a-methylhydratropic Acid
Carebastinum carebastine 2-(4-{4-[4-(Diphenylmethoxy)piperidin-1-yl]butanoyl}phenyl)-2-methylpropanoic acid 4-(4-(4-(Diphenylmethoxy)-1-piperidinyl)-1-oxobutyl)-a,a-dimethylbenzeneacetic Acid Benzeneacetic acid, 4-[4-[4-(diphenylmethoxy)-1-piperidinyl]-1-oxobutyl]-α,α-dimethyl- Carebastina C32H37NO4 UNII-75DLN707DO 2-(4-{4-[4-(Diphenylmethoxy)-1-piperidinyl]butanoyl}phenyl)-2-methylpropanoic acid |
Description | Carebastine is the active metabolite of Ebastine. Carebastine is a histamine H1 receptor antagonist. Carebastine inhibits VEGF-induced HUVEC and HPAEC proliferation, migration and angiogenesis in a dose-dependent manner[1]. Carebastine suppresses the expression of macrophage migration inhibitory factor[2]. |
---|---|
Related Catalog | |
Target |
H1 receptor |
References |
Density | 1.2±0.1 g/cm3 |
---|---|
Boiling Point | 657.9±55.0 °C at 760 mmHg |
Melting Point | 178-180ºC |
Molecular Formula | C32H37NO4 |
Molecular Weight | 499.641 |
Flash Point | 351.7±31.5 °C |
Exact Mass | 499.272247 |
PSA | 66.84000 |
LogP | 6.09 |
Vapour Pressure | 0.0±2.1 mmHg at 25°C |
Index of Refraction | 1.609 |