21416-68-2

21416-68-2 structure

21416-68-2 structure

Name: ICRF-196
Chemical Name: 4-[3-(3,5-dioxopiperazin-1-yl)butan-2-yl]piperazine-2,6-dione
CAS Number: 21416-68-2
Molecular Formula: C₁₂H₁₈N₄O₄
Molecular Weight: 282.30
Create Date: 2017-06-04 23:42:14
Modify Date: 2024-01-21 17:48:32
ICRF-196 is an racemic mixture of the (S,S)- and (R,R)-isomers of ICRF-193 (HY-118590). ICRF-193 is an TopoII inhibitor. ICRF-196 can be used for the research of cancer[1].

Name	4-[3-(3,5-dioxopiperazin-1-yl)butan-2-yl]piperazine-2,6-dione
Synonyms	C12H18N4O4 Icrf 193

Description	ICRF-196 is an racemic mixture of the (S,S)- and (R,R)-isomers of ICRF-193 (HY-118590). ICRF-193 is an TopoII inhibitor. ICRF-196 can be used for the research of cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
References	[1]. Snapka RM,et al. Inhibition of topoisomerase II by ICRF-193, the meso isomer of 2,3-bis(2,6-dioxopiperazin-4-yl)butane. Critical dependence on 2,3-butanediyl linker absolute configuration. Biochem Pharmacol. 1996;52(4):543-549.

Density	1.308g/cm3
Boiling Point	526.7ºC at 760mmHg
Molecular Formula	C₁₂H₁₈N₄O₄
Molecular Weight	282.30
Flash Point	272.4ºC
Exact Mass	282.13300
PSA	98.82000
Vapour Pressure	3.48E-11mmHg at 25°C
Index of Refraction	1.539

HS Code	2933599090

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%