35803-45-3

35803-45-3 structure
35803-45-3 structure
  • Name: Uracil-13C
  • Chemical Name: 1H-pyrimidine-2,4-dione-13C
  • CAS Number: 35803-45-3
  • Molecular Formula: C4H4N2O2
  • Molecular Weight: 113.07900
  • Catalog: Research Areas Cancer
  • Create Date: 2018-03-29 08:00:00
  • Modify Date: 2024-01-10 16:16:50
  • Uracil-13C is the 13C labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].

Name 1H-pyrimidine-2,4-dione-13C
Synonyms Uracil-2-13C
Uracil (2-13C) (JAN)
2-[(13)C]uracil
MFCD00084096
Description Uracil-13C is the 13C labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Pałasz A, et al. In search of uracil derivatives as bioactive agents. Uracils and fused uracils: Synthesis, biological activity and applications. Eur J Med Chem. 2015 Jun 5;97:582-611.  

Density 1.322g/cm3
Melting Point >300ºC (dec.)(lit.)
Molecular Formula C4H4N2O2
Molecular Weight 113.07900
Exact Mass 113.03100
PSA 65.72000
Index of Refraction 1.502
RIDADR NONH for all modes of transport
WGK Germany 3

~65%

35803-45-3 structure

35803-45-3

Literature: Iida, Katsumi; Chiyoda, Takeshi; Hirasawa, Ryo; Iwata, Akiko; Kajiwara, Masahiro Journal of Labelled Compounds and Radiopharmaceuticals, 1997 , vol. 39, # 1 p. 69 - 77
Precursor  2

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