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Product Name: Diacetolol
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22568-64-5

22568-64-5 structure

22568-64-5 structure

Name: Diacetolol
Chemical Name: rac Diacetolol
CAS Number: 22568-64-5
Molecular Formula: C₁₆H₂₄N₂O₄
Molecular Weight: 308.37
Catalog: analytical chemistry Standard Pharmacopoeia Standards and Magazine Standards
Create Date: 2018-06-21 17:01:15
Modify Date: 2024-01-11 14:44:33
Diacetolol is an active metabolite of the beta-adrenoceptor blocking agent Acebutolol (HY-17497)[1].

Name	rac Diacetolol
Synonyms	N-{3-Acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl}acetamide N-{3-Acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl}acetami de Acebutolol impurity B N-{3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide N-{3-Acetyl-4-{(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy}phenyl}acetamide Acetamide, N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]- Diacetolol EINECS 245-088-3

Description	Diacetolol is an active metabolite of the beta-adrenoceptor blocking agent Acebutolol (HY-17497)[1].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Endocrinology
References	[1]. B Basil, R Jordan, et al. Pharmacological properties of diacetolol (M & B 16,942), a major metabolite of acebutolol. Eur J Pharmacol. 1982 May 7;80(1):47-56.

Density	1.2±0.1 g/cm3
Boiling Point	548.8±50.0 °C at 760 mmHg
Molecular Formula	C₁₆H₂₄N₂O₄
Molecular Weight	308.37
Flash Point	285.7±30.1 °C
Exact Mass	308.173615
PSA	91.15000
LogP	0.89
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.551
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AB4205000

CHEMICAL NAME :: Acetamide, N-(3-acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)prop oxy)phenyl)-, (+-)-

CAS REGISTRY NUMBER :: 22568-64-5

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C16-H24-N2-O4

MOLECULAR WEIGHT :: 308.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 77600 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NPMDAD Nouvelle Presse Medicale. (Paris, France) V.1-11, 1972-82. Volume(issue)/page/year: 7,3258,1978

RIDADR	NONH for all modes of transport
HS Code	2924299090

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%