629-13-0

629-13-0 structure

Name: Azide-C2-Azide
Chemical Name: 1,2-Diazidoethane
CAS Number: 629-13-0
Molecular Formula: C₂H₄N₆
Molecular Weight: 112.09300
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2017-05-15 22:36:14
Modify Date: 2024-01-09 19:35:43
Azide-C2-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	1,2-Diazidoethane
Synonyms	Aethylendiazid Ethane,1,2-diazido 1,2-Diazido-aethan 1,2-diazido-ethane 1.2-Diazo-aethan Aethylenazid

Description	Azide-C2-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Formula	C₂H₄N₆
Molecular Weight	112.09300
Exact Mass	112.05000
PSA	99.50000
LogP	0.51252

106-93-4

~72%

629-13-0

Literature: Betzler, Franziska M.; Klapoetke, Thomas M.; Sproll, Stefan M. European Journal of Organic Chemistry, 2013 , # 3 p. 509 - 514

107-06-2

~73%

629-13-0

Literature: Vereshchagin, L. I.; Tikhonova, L. G.; Maksikova, A. V.; Serebryakova, E. S.; Proidakov, A. G.; Filippova, T. M. Journal of Organic Chemistry USSR (English Translation), 1980 , vol. 16, # 4 p. 641 - 648 Zhurnal Organicheskoi Khimii, 1980 , vol. 16, # 4 p. 730 - 738

Precursor 2
106-93-4 107-06-2
DownStream 1
107-15-3

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