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149577-05-9

149577-05-9 structure
149577-05-9 structure
  • Name: m-PEG2-acid
  • Chemical Name: 3-(2-methoxyethoxy)propanoic acid
  • CAS Number: 149577-05-9
  • Molecular Formula: C6H12O4
  • Molecular Weight: 148.15700
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-07-21 15:51:57
  • Modify Date: 2024-01-19 15:05:44
  • m-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name 3-(2-methoxyethoxy)propanoic acid
Synonyms MFCD09939037
Description m-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

Molecular Formula C6H12O4
Molecular Weight 148.15700
Exact Mass 148.07400
PSA 55.76000
LogP 0.12410
HS Code 2918990090
HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%