173352-39-1
173352-39-1 structure
- Name: Fabomotizole (hydrochloride)
- Chemical Name: 4-[2-[(6-ethoxy-1H-benzimidazol-2-yl)sulfanyl]ethyl]morpholine,hydrochloride
- CAS Number: 173352-39-1
- Molecular Formula: C15H22ClN3O2S
- Molecular Weight: 343.87200
- Catalog: Research Areas Neurological Disease
- Create Date: 2017-03-24 12:14:46
- Modify Date: 2024-01-13 02:50:40
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Fabomotizole Hcl (CM346 Hcl) is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions.IC50 value:Target: anxiolytic agent Afobazole's mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA.
| Name | 4-[2-[(6-ethoxy-1H-benzimidazol-2-yl)sulfanyl]ethyl]morpholine,hydrochloride |
|---|---|
| Synonyms |
UNII-HDO6HX6NZU
Afobazol Aphobazole HDO6HX6NZU Afobazole Fabomotizole (hydrochloride) |
| Description | Fabomotizole Hcl (CM346 Hcl) is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions.IC50 value:Target: anxiolytic agent Afobazole's mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C15H22ClN3O2S |
|---|---|
| Molecular Weight | 343.87200 |
| Exact Mass | 343.11200 |
| PSA | 75.68000 |
| LogP | 3.12580 |