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80277-11-8

80277-11-8 structure
80277-11-8 structure

Name N-[4-(acridin-9-ylamino)-3-methoxy-phenyl]methanesulfonamide: 2-hydrox ypropanoic acid
Synonyms m-Amsa lactate
Amsacrine lactate
Boiling Point 563ºC at 760 mmHg
Molecular Formula C24H25N3O6S
Molecular Weight 483.53700
Flash Point 294.3ºC
Exact Mass 483.14600
PSA 146.23000
LogP 5.19030

CHEMICAL IDENTIFICATION

RTECS NUMBER :
PB0394000
CHEMICAL NAME :
Methanesulfonamide, N-(4-(9-acridinylamino)-3-methoxyphenyl)-, mono(2-hydroxypropanoate)
CAS REGISTRY NUMBER :
80277-11-8
LAST UPDATED :
198910
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C21-H19-N3-O3-S.C3-H6-O3
MOLECULAR WEIGHT :
483.58

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
5 mg/kg
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 35,76A,1987
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
10 mg/kg
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 35,76A,1987
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