827030-33-1
827030-33-1 structure
- Name: 2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine
- Chemical Name: 2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine
- CAS Number: 827030-33-1
- Molecular Formula: C16H14ClN3O
- Molecular Weight: 299.75500
- Create Date: 2016-11-02 15:53:58
- Modify Date: 2024-01-30 20:27:05
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MPI-0441138 is a potent inducer of apoptosis and growth inhibition (EC50 = 2 nM for both processes, based on caspase-3 activation and total cellular ATP, respectively) in T47D and HCT116 cells.
| Name | 2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine |
|---|
| Molecular Formula | C16H14ClN3O |
|---|---|
| Molecular Weight | 299.75500 |
| Exact Mass | 299.08300 |
| PSA | 38.25000 |
| LogP | 4.05970 |
|
~85%
827030-33-1 |
| Literature: Sirisoma, Nilantha; Kasibhatla, Shailaja; Pervin, Azra; Zhang, Hong; Jiang, Songchun; Willardsen, J. Adam; Anderson, Mark B.; Baichwal, Vijay; Mather, Gary G.; Jessing, Kevin; Hussain, Raouf; Hoang, Khanh; Pleiman, Christopher M.; Tseng, Ben; Drewe, John; Sui, Xiong Cai Journal of Medicinal Chemistry, 2008 , vol. 51, # 15 p. 4771 - 4779 |
