62956-48-3

62956-48-3 structure

Name: gomisin G
Chemical Name: gomisin G
CAS Number: 62956-48-3
Molecular Formula: C₃₀H₃₂O₉
Molecular Weight: 536.570
Catalog: Biochemical Plant extracts
Create Date: 2018-05-09 08:00:00
Modify Date: 2024-01-03 10:11:16
Gomisin G is an ethanolic extract of the stems of Kadsura interior; exhibits potent anti-HIV activity with EC50 and therapeutic index (TI) values of 0.006 microgram/mL and 300, respectively.

Name	gomisin G
Synonyms	(6S,7S,8S)-7-Hydroxy-1,2,3,13-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-8-yl benzoate UNII:6B4CV8T31X Benzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxole-7,8-diol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, 8-benzoate, (6S,7S,8S)- The dried fruit of Schisandra chinensis

Description	Gomisin G is an ethanolic extract of the stems of Kadsura interior; exhibits potent anti-HIV activity with EC50 and therapeutic index (TI) values of 0.006 microgram/mL and 300, respectively.
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Natural Products >> Phenylpropanoids Research Areas >> Infection
References	[1]. Chen DF, et al. Anti-AIDS agents--XXVI. Structure-activity correlations of gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues. Bioorg Med Chem. 1997 Aug;5(8):1715-23. [2]. Ikeya Y, et al. The constituents of Schizandra chinensis Baill. I. Isolation and structure determination of five new lignans, gomisin A, B, C, F and G, and the absolute structure of schizandrin. Chem Pharm Bull (Tokyo). 1979 Jun;27(6):1383-94.