| Name | hastatoside |
|---|---|
| Synonyms | Methyl (1S,4aR,7S,7aR)-1-(β-D-glucopyranosyloxy)-4a-hydroxy-7-methyl-5-oxo-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate |
| Description | Hastatoside is an iridoid glycoside that is isolated from Verbena officinalis and has a role in promoting sleep[1]. |
|---|---|
| Related Catalog | |
| In Vivo | Hastatoside (0.32-0.64 mmol/kg; oral administration; for 9 hours; male rats of the Sprague-Dawley strain) treatment increases the total time of non-rapid eye movement sleep during a 9-h period, with a lag time of about 3-5 h after the administration at 20. 00 hours (lights-off time). Hastatoside also increases the delta activity during non-rapid eye movement sleep[1]. Animal Model: Male rats of the Sprague-Dawley strain (8 weeks old; 260-280 g)[1] Dosage: 0.32 mmol/kg, 0.48 mmol/kg, 0.64 mmol/kg Administration: Oral administration; for 9 hours Result: Increased the total time of non-rapid eye movement sleep during a 9-h period, with a lag time of about 3-5 h after the administration at 20. 00 hours (lights-off time). Also increased the delta activity during non-rapid eye movement sleep. |
| References |
[1]. uki MAKINO, et al. Hastatoside and verbenalin are sleep-promoting |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 653.5±55.0 °C at 760 mmHg |
| Molecular Formula | C17H24O11 |
| Molecular Weight | 404.366 |
| Flash Point | 234.8±25.0 °C |
| Exact Mass | 404.131866 |
| PSA | 172.21000 |
| LogP | -2.38 |
| Vapour Pressure | 0.0±4.5 mmHg at 25°C |
| Index of Refraction | 1.613 |
| Storage condition | 2-8C |