50816-24-5

50816-24-5 structure

Name: Hastatoside
Chemical Name: hastatoside
CAS Number: 50816-24-5
Molecular Formula: C₁₇H₂₄O₁₁
Molecular Weight: 404.366
Catalog: Signaling Pathways Others Others
Create Date: 2018-05-30 08:00:00
Modify Date: 2024-01-07 07:13:48
Hastatoside is an iridoid glycoside that is isolated from Verbena officinalis and has a role in promoting sleep[1].

Name	hastatoside
Synonyms	Methyl (1S,4aR,7S,7aR)-1-(β-D-glucopyranosyloxy)-4a-hydroxy-7-methyl-5-oxo-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-4a-hydroxy-7-methyl-5-oxo-, methyl ester, (1S,4aR,7S,7aR)-

Description	Hastatoside is an iridoid glycoside that is isolated from Verbena officinalis and has a role in promoting sleep[1].
Related Catalog	Signaling Pathways >> Others >> Others
In Vivo	Hastatoside (0.32-0.64 mmol/kg; oral administration; for 9 hours; male rats of the Sprague-Dawley strain) treatment increases the total time of non-rapid eye movement sleep during a 9-h period, with a lag time of about 3-5 h after the administration at 20. 00 hours (lights-off time). Hastatoside also increases the delta activity during non-rapid eye movement sleep[1]. Animal Model: Male rats of the Sprague-Dawley strain (8 weeks old; 260-280 g)[1] Dosage: 0.32 mmol/kg, 0.48 mmol/kg, 0.64 mmol/kg Administration: Oral administration; for 9 hours Result: Increased the total time of non-rapid eye movement sleep during a 9-h period, with a lag time of about 3-5 h after the administration at 20. 00 hours (lights-off time). Also increased the delta activity during non-rapid eye movement sleep.
References	[1]. uki MAKINO, et al. Hastatoside and verbenalin are sleep-promoting