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132682-98-5

132682-98-5 structure
132682-98-5 structure
  • Name: Glufosfamide
  • Chemical Name: (2S,3R,4S,5S,6R)-2-bis(2-chloroethylamino)phosphoryloxy-6-(hydroxymethyl)oxane-3,4,5-triol
  • CAS Number: 132682-98-5
  • Molecular Formula: C10H21Cl2N2O7P
  • Molecular Weight: 383.163
  • Catalog: Research Areas Cancer
  • Create Date: 2018-02-10 08:00:00
  • Modify Date: 2024-01-09 14:56:12
  • Glufosfamide is a novel alkylating agent in which the active metabolite of isophosphoramide mustard is glycosidically linked to β-D-glucose.

Name (2S,3R,4S,5S,6R)-2-bis(2-chloroethylamino)phosphoryloxy-6-(hydroxymethyl)oxane-3,4,5-triol
Synonyms β-D-glucosyl-ifosfamide mustard
glc-IPM
β-D-Glucopyranose, 1-O-[bis[(2-chloroethyl)amino]phosphinyl]-
UNII-1W5N8SZD9A
b-D-Glucopyranose 1-(N,N'-Bis(2-chloroethyl)phosphorodiamidate)
Glucosylifostamide mustard
1-O-{Bis[(2-chloroethyl)amino]phosphoryl}-β-D-glucopyranose
Glufosfamide
Glucosyl-ifosfamide mustard
Description Glufosfamide is a novel alkylating agent in which the active metabolite of isophosphoramide mustard is glycosidically linked to β-D-glucose.
Related Catalog
References

[1]. DollnerR, et al. Ex vivo responsiveness of head and neck squamous cell carcinoma to glufosfamide, a novelalkylating agent. Anticancer Res. 2004 Sep-Oct;24(5A):2947-51.

Density 1.6±0.1 g/cm3
Boiling Point 569.9±60.0 °C at 760 mmHg
Molecular Formula C10H21Cl2N2O7P
Molecular Weight 383.163
Flash Point 298.5±32.9 °C
Exact Mass 382.046356
PSA 150.32000
LogP -1.07
Vapour Pressure 0.0±3.6 mmHg at 25°C
Index of Refraction 1.563

~91%

132682-98-5 structure

132682-98-5

Literature: THRESHOLD PHARMACEUTICALS, INC. Patent: WO2008/11588 A2, 2008 ; Location in patent: Page/Page column 35 ;