252198-68-8
252198-68-8 structure
- Name: CGH2466
- Chemical Name: 4-(3,4-dichlorophenyl)-5-pyridin-4-yl-1,3-thiazol-2-amine
- CAS Number: 252198-68-8
- Molecular Formula: C14H11Cl4N3S
- Molecular Weight: 395.13400
- Create Date: 2016-05-04 12:20:08
- Modify Date: 2024-01-13 14:18:17
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A combined adenosine receptor antagonist, p38 MAPK and PDE4 inhibitor, inhibits A1, A2b and A3 receptor (IC50=19, 21 and 80 nM), p38α, p38β and PDE4D (IC50=87, 400 and 22 nM).
| Name | 4-(3,4-dichlorophenyl)-5-pyridin-4-yl-1,3-thiazol-2-amine |
|---|---|
| Synonyms | cgh 2466 |
| Density | 1.45g/cm3 |
|---|---|
| Boiling Point | 480.5ºC at 760mmHg |
| Molecular Formula | C14H11Cl4N3S |
| Molecular Weight | 395.13400 |
| Flash Point | 244.4ºC |
| Exact Mass | 392.94300 |
| PSA | 80.04000 |
| LogP | 6.94630 |
| Vapour Pressure | 2.16E-09mmHg at 25°C |
| Index of Refraction | 1.68 |