Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Galanin (human) acetate salt
Price: ￥2018.0/1mg ￥5638.0/5mg
Purity: 97.0%
Stocking Period: Inquiry
Contact: Liu jia

119418-04-1

119418-04-1 structure

119418-04-1 structure

Name: Galanin (human) acetate salt
Chemical Name: Galanin human
CAS Number: 119418-04-1
Molecular Formula: C₁₃₉H₂₁₀N₄₂O₄₃
Molecular Weight: 3157.41000
Catalog: Peptides
Create Date: 2018-07-14 10:39:07
Modify Date: 2024-01-02 17:11:32
Galanin (1-30), human is a 30-amino acid neuropeptide, and acts as an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM.

Name	Galanin human
Synonyms	MFCD00135986 Galanin,Human Galanin-1-30 Galanin (1-30), human

Description	Galanin (1-30), human is a 30-amino acid neuropeptide, and acts as an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor Peptides Research Areas >> Neurological Disease
Target	Kd: 1 nM (GalR1 receptor), 1 nM (GalR2 receptor)[2]
In Vitro	Galanin (1-30), human (Gal1-30) is an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM[1]. Galanin (1-30), human displaces 125I-labeled rat galanin with a Kd of 0.5 nM. Galanin (1-30), human (hGal) causes contractions of isolated longitudinal rat fundus strips, with an ED50 of 13.8 ± 1.6 nM[2].
References	[1]. Hua XY, et al. Galanin acts at GalR1 receptors in spinal antinociception: synergy with morphine and AP-5. J Pharmacol Exp Ther. 2004 Feb;308(2):574-82. [2]. Schmidt WE, et al. Isolation and primary structure of pituitary human galanin, a 30-residue nonamidated neuropeptide. Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11435-9.

Molecular Formula	C₁₃₉H₂₁₀N₄₂O₄₃
Molecular Weight	3157.41000
Exact Mass	3155.55000
PSA	1367.68000

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