357336-20-0
357336-20-0 structure
- Name: Brivaracetam
- Chemical Name: (2S)-2-[(4R)-2-oxo-4-propylpyrrolidin-1-yl]butanamide
- CAS Number: 357336-20-0
- Molecular Formula: C11H20N2O2
- Molecular Weight: 212.289
- Catalog: API Nervous system medication Brain metabolism regulating drug
- Create Date: 2018-06-30 23:16:23
- Modify Date: 2025-08-24 16:30:38
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Brivaracetam(UCB-34714) is a 4-substituted pyrrolidone butanamide as agent with significant antiepileptic activity; high affinity SV2A ligand and also shows an ability to inhibit Na+ channels.
| Name | (2S)-2-[(4R)-2-oxo-4-propylpyrrolidin-1-yl]butanamide |
|---|---|
| Synonyms |
Briviact
(2S)-2-[(4R)-2-Oxo-4-propyl-1-pyrrolidinyl]butanamide 1-Pyrrolidineacetamide, α-ethyl-2-oxo-4-propyl-, (αS,4R)- Rikelta UCB 34714 UCB34714 Brivaracetam |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 409.3±28.0 °C at 760 mmHg |
| Melting Point | 76.38° |
| Molecular Formula | C11H20N2O2 |
| Molecular Weight | 212.289 |
| Flash Point | 201.3±24.0 °C |
| Exact Mass | 212.152481 |
| PSA | 63.40000 |
| LogP | 0.88 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.494 |
| HS Code | 2933990090 |
|---|
|
~%
357336-20-0 |
| Literature: UCB S.A. Patent: WO2007/31263 A1, 2007 ; Location in patent: Page/Page column 31 ; |
|
~%
357336-20-0 |
| Literature: Kenda, Benoit M.; Matagne, Alain C.; Talaga, Patrice E.; Pasau, Patrick M.; Differding, Edmond; Lallemand, Benedicte I.; Frycia, Anne M.; Moureau, Florence G.; Klitgaard, Henrik V.; Gillard, Michel R.; Fuks, Bruno; Michel, Philippe Journal of Medicinal Chemistry, 2004 , vol. 47, # 3 p. 530 - 549 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |