915769-50-5

915769-50-5 structure

Name: Dovitinib lactate
Chemical Name: CHIR-258
CAS Number: 915769-50-5
Molecular Formula: C₂₄H₂₉FN₆O₅
Molecular Weight: 500.523
Catalog: API Antineoplastic agents Tinic antineoplastic agents
Create Date: 2018-07-24 16:37:55
Modify Date: 2025-09-22 11:32:54
Dovitinib (TKI258, CHIR258) is a novel multi-target inhibitor for Flt3, c-Kit, FGFR1/3, VEGFR1/2/3, PDGFRα/β with IC50 of 1 nM, 2 nM, 8 nM/9 nM and 10 nM/13 nM/8 nM, 210 nM/27 nM respectively.

Name	CHIR-258
Synonyms	Dovitinib lactate 2-Hydroxypropanoic acid - 4-amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone hydrate (1:1:1) Unii-69vky8p7ea Propanoic acid, 2-hydroxy-, compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone, hydrate (1:1:1) dovitinib TKI-258