Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-Piperidinecarboxamide,4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-N,N-dimethyl-
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Purity: 98.0%
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1580-71-8

1580-71-8 structure

1580-71-8 structure

Name: 4-Piperidinecarboxamide,4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-N,N-dimethyl-
Chemical Name: 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-N,N-dimethylpiperidine-4-carboxamide
CAS Number: 1580-71-8
Molecular Formula: C₂₄H₂₈ClFN₂O₂
Molecular Weight: 430.94300
Create Date: 2018-08-28 09:12:06
Modify Date: 2024-01-11 22:07:31

Name	4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-N,N-dimethylpiperidine-4-carboxamide
Synonyms	Amiperone 4-(4-chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-oxo-butyl]-piperidine-4-carboxylic acid dimethylamide R 2962 Paraperidine Paraperidide Amiperona [INN-Spanish] Amiperonum [INN-Latin]

Density	1.192g/cm3
Boiling Point	578.8ºC at 760mmHg
Molecular Formula	C₂₄H₂₈ClFN₂O₂
Molecular Weight	430.94300
Flash Point	303.8ºC
Exact Mass	430.18200
PSA	40.62000
LogP	4.50190
Vapour Pressure	2.16E-13mmHg at 25°C
Index of Refraction	1.56

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NS4970000

CHEMICAL NAME :: Isonipecotamide, 4-(p-chlorophenyl)-1-(3-(p-fluorobenzoyl)propyl)-N,N- dimethyl-

CAS REGISTRY NUMBER :: 1580-71-8

BEILSTEIN REFERENCE NO. :: 0501454

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C24-H28-Cl-F-N2-O2

MOLECULAR WEIGHT :: 430.99

WISWESSER LINE NOTATION :: T6NTJ A3VR DF& DVN1&1 DR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >160 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 29 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972 *** REVIEWS *** TOXICOLOGY REVIEW MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 4(2),199,1967