Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,2-Ethanediamine,N1,N1-dimethyl-N2-phenyl-N2-(phenylmethyl)-, hydrochloride (1:1)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Contact: Ms Wang

2045-52-5

2045-52-5 structure

2045-52-5 structure

Name: 1,2-Ethanediamine,N1,N1-dimethyl-N2-phenyl-N2-(phenylmethyl)-, hydrochloride (1:1)
Chemical Name: N'-benzyl-N,N-dimethyl-N'-phenylethane-1,2-diamine,hydrochloride
CAS Number: 2045-52-5
Molecular Formula: C₁₇H₂₃ClN₂
Molecular Weight: 290.83100
Create Date: 2016-06-09 08:23:03
Modify Date: 2024-04-04 23:15:43

Name	N'-benzyl-N,N-dimethyl-N'-phenylethane-1,2-diamine,hydrochloride
Synonyms	PHENBENZAMINE HYDROCHLORIDE 2339 R.P. hydrochloride Compound 2339 RP Antergan hydrochloride N-benzyl-N',N'-dimethyl-N-phenyl-ethylenediamine,hydrochloride Phenbenzamine chloride N-Phenyl-N-benzyl-N',N'-dimethylethylenediamine hydrochloride N-benzyl-N',N'-dimethyl-N-phenyl-ethylenediamine,monohydrochloride N-Benzyl-N',N'-dimethyl-N-phenyl-aethylendiamin,Monohydrochlorid N-Benzyl-N',N'-dimethyl-N-phenyl-aethylendiamin,Hydrochlorid Corps 2339 R P

Boiling Point	375.9ºC at 760 mmHg
Melting Point	210 - 211ºC
Molecular Formula	C₁₇H₂₃ClN₂
Molecular Weight	290.83100
Flash Point	166.2ºC
Exact Mass	290.15500
PSA	6.48000
LogP	4.05680
Vapour Pressure	7.52E-06mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KV1925000

CHEMICAL NAME :: Ethylenediamine, N-benzyl-N',N'-dimethyl-N-phenyl-, hydrochloride

CAS REGISTRY NUMBER :: 2045-52-5

LAST UPDATED :: 199109

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C17-H22-N2.Cl-H

MOLECULAR WEIGHT :: 290.87

WISWESSER LINE NOTATION :: 1N1&2NR&1R &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Behavioral - muscle contraction or spasticity

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 68,339,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 144,887,1950

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 325 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,210,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 125 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,210,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 35 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,210,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 15 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,210,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 110 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 27,542,1947