42204-43-3
42204-43-3 structure
- Name: [5-(6-aminopurin-9-yl)-3-hydroxy-oxolan-2-yl]methylimino-imino-azanium
- Chemical Name: 5'-Azido-2',5'-didesoxy-adenosin
- CAS Number: 42204-43-3
- Molecular Formula: C10H12N8O2
- Molecular Weight: 276.25
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2017-10-11 20:09:04
- Modify Date: 2024-01-11 18:40:26
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5′-Azido-2′,5′-dideoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 5'-Azido-2',5'-didesoxy-adenosin |
|---|---|
| Synonyms |
5'-azido-2',5'-dideoxyadenosine
5'-azido-5'-deoxy-2',3'-O-isopropylideneguanosine 5'-azido-2',3'-O-isopropylideneguanosine 5'-azido-O2',O3'-isopropylidene-5'-deoxy-guanosine 5'-azido-5',2'-dideoxyadenosine 2',3'-O-Isopropyliden-5'-azido-5'-desoxy-guanosin |
| Description | 5′-Azido-2′,5′-dideoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C10H12N8O2 |
|---|---|
| Molecular Weight | 276.25 |
| Exact Mass | 276.10800 |
| PSA | 148.83000 |
| LogP | 0.40116 |
|
~76%
42204-43-3 |
| Literature: Mattarella, Martin; Berstis, Laura; Baldridge, Kim K.; Siegel, Jay S. Bioconjugate Chemistry, 2014 , vol. 25, # 1 p. 115 - 128 |
|
~%
42204-43-3 |
| Literature: Schmidt; Pedersen; Nielsen Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1994 , vol. 48, # 3 p. 215 - 221 |
|
~%
42204-43-3 |
| Literature: Schmidt; Pedersen; Nielsen Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1994 , vol. 48, # 3 p. 215 - 221 |
|
~%
42204-43-3 |
| Literature: Schmidt; Pedersen; Nielsen Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1994 , vol. 48, # 3 p. 215 - 221 |
|
~%
42204-43-3 |
| Literature: Schmidt; Pedersen; Nielsen Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1994 , vol. 48, # 3 p. 215 - 221 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |